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Record W1523694814 · doi:10.5772/19898

Enhancing the Performance of Surface-based Biosensors by AC Electrokinetic Effects - a Review

2011· review· en· W1523694814 on OpenAlexaff
Protiva Rani, Matthew R. Tomkins, Aristides Docoslis

Bibliographic record

VenueInTech eBooks · 2011
Typereview
Languageen
FieldEngineering
TopicMicrofluidic and Bio-sensing Technologies
Canadian institutionsQueen's University
Fundersnot available
KeywordsElectrokinetic phenomenaBiosensorNanotechnologySurface (topology)Materials scienceMathematics

Abstract

fetched live from OpenAlex

Miniaturized surface based biosensors are a cost effective and portable means for the sensing of biologically active compounds. With advents in micro-and nanotechnology, the design of surface based biosensors can be adapted for various detection goals and for integration with multiple detection techniques. In particular, the issue of pathogen detection is an important challenge with applications in defence, health care, food safety, diagnostics and clinical research. The research of micro-fluidic analytical systems, such as surface based biosensors or "lab-on-a-chip" designs, have gained increasing popularity, not only due to the enhancement of the analytical performance, but also due to their reduced size, decreased consumption of reagents and the ability to integrate multiple technologies within a single device. Although conventional pathogen detection methods are well established, they are greatly restricted by the assay time. For pathogens that typically occur at low concentrations, the mass transfer required for detection is diffusion limited and incubation is often needed in order to enhance the concentration of the target analyte. AC electrokinetic effects provide a means for biosensors to detect pathogens quickly and at lower concentrations, thus overcoming these bottlenecks.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.770
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.236
Teacher spread0.220 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designOther design
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2011
Admission routes1
Has abstractyes

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