Olfactory Ensheathing Cells: Isolation and Culture from the Neonatal Olfactory Bulb
Bibliographic record
Abstract
Olfactory ensheathing cells (OECs), which are glia from the olfactory system, have evolved as attractive candidates for transplant-mediated repair based on long-standing knowledge that the olfactory system is one of the only central nervous system tissues that can support neurogenesis throughout life. After injury and during normal cell turnover, the olfactory receptor neurons (ORNs) die, and new nerves are generated from putative stem cells in the olfactory epithelium. OECs, which reside throughout the olfactory system, guide the ORN axons as they travel through the olfactory mucosa (olfactory epithelium and lamina propria) and the cribriform plate, terminating in synapse formation in the usually nonpermissive environment of the olfactory bulb. It is this ability to support axonal outgrowth throughout life that has made olfactory tissue such a promising focus for repair strategies. Here, we provide a method to purify OECs-from the rat olfactory bulb and in Chapter 9, from the turbinates of the mouse olfactory epithelium.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".