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The Alberta Pregnancy Outcomes and Nutrition (APrON) cohort study: rationale and methods

2012· article· en· W1528405876 on OpenAlexafffundabout
Bonnie J. Kaplan, Gerald F. Giesbrecht, Brenda Leung, Catherine J. Field, Deborah Dewey, Rhonda C. Bell, Donna Manca, Maeve O’Beirne, David Johnston, Victor J.M. Pop, Nalini Singhal, Lisa Gagnon, François P. Bernier, Misha Eliasziw, Linda J. McCargar, Libbe Kooistra, Anna Farmer, Marja Cantell, L. A. Goonewardene, Linda Casey, Nicole Letourneau, Jonathan W. Martin

Bibliographic record

VenueMaternal and Child Nutrition · 2012
Typearticle
Languageen
FieldMedicine
TopicGestational Diabetes Research and Management
Canadian institutionsUniversity of CalgaryUniversity of Alberta
FundersAlberta Children's Hospital Research InstituteAlberta InnovatesWomen and Children's Health Research InstituteChildren's Health Research InstituteAlberta Health Services
KeywordsMedicinePregnancyAnthropometryOffspringProspective cohort studyCohort studyCohortObstetricsMoodEnvironmental healthPediatricsPsychiatry

Abstract

fetched live from OpenAlex

The Alberta Pregnancy Outcomes and Nutrition (APrON) study is an ongoing prospective cohort study that recruits pregnant women early in pregnancy and, as of 2012, is following up their infants to 3 years of age. It has currently enrolled approximately 5000 Canadians (2000 pregnant women, their offspring and many of their partners). The primary aims of the APrON study were to determine the relationships between maternal nutrient intake and status, before, during and after gestation, and (1) maternal mood; (2) birth and obstetric outcomes; and (3) infant neurodevelopment. We have collected comprehensive maternal nutrition, anthropometric, biological and mental health data at multiple points in the pregnancy and the post-partum period, as well as obstetrical, birth, health and neurodevelopmental outcomes of these pregnancies. The study continues to follow the infants through to 36 months of age. The current report describes the study design and methods, and findings of some pilot work. The APrON study is a significant resource with opportunities for collaboration.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.017
metaresearch head score (Gemma)0.011
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Protocol · Consensus signal: Protocol
Teacher disagreement score0.300
Threshold uncertainty score0.597

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0170.011
Meta-epidemiology (narrow)0.0020.002
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0040.007
Science and technology studies0.0040.003
Scholarly communication0.0020.001
Open science0.0050.002
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0060.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.313
Teacher spread0.301 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreProtocol

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations179
Published2012
Admission routes3
Has abstractyes

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