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Record W1531353448 · doi:10.1159/000095331

Treatment of Obesity: A Challenging Task

2006· review· en· W1531353448 on OpenAlex
Arya M. Sharma, Gianluca Iacobellis

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueContributions to nephrology · 2006
Typereview
Languageen
FieldMedicine
TopicPharmacology and Obesity Treatment
Canadian institutionsMcMaster UniversityHamilton Health Sciences
Fundersnot available
KeywordsWeight lossOrlistatSibutramineMedicineObesityManagement of obesityWeight managementPsychological interventionPhysical therapyIntensive care medicineInternal medicinePsychiatry

Abstract

fetched live from OpenAlex

BACKGROUND: Obesity is a chronic and heterogeneous medical condition. Weight loss is clearly the most desirable goal in obese subjects management. Successful obesity treatment should be defined as long-term weight loss maintenance. In this chapter, we briefly review the current evidences regarding the treatment of obesity. METHODS: We searched MEDLINE and PubMed for original articles published between 1995 and 2006, focusing on obesity treatment. The search terms we used, alone or in combination, were 'obesity', 'lifestyle changes', 'diet', 'exercise', 'pharmacological treatment', 'surgical treatment'. CONCLUSIONS: The conventional management of obese patients involves weight reduction with lifestyle changes, including dietary therapy and increased physical activity, or a combined approach with lifestyle changes and pharmacological or surgical interventions. Exercise appears crucial in the successful maintenance of weight loss and in fostering cardiovascular health in obese patients. Some anti-obesity drugs, such as sibutramine and orlistat, have been shown to induce a significant weight loss and long-term weight loss maintenance. Surgical therapy is often necessary in morbidly obese patients and generally results in more significant and long-lasting weight loss than other treatments.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.977
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0030.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.036
GPT teacher head0.389
Teacher spread0.353 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it