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Record W1535377188 · doi:10.1002/jppr200434111

Stability of Insulin Aspart in Normal Saline Infusion

2004· article· en· W1535377188 on OpenAlexaff
Stephen Lim, Malcolm Roberts, M. J. Paech, Peng Li, Allan Jones

Bibliographic record

VenueJournal of Pharmacy Practice and Research · 2004
Typearticle
Languageen
FieldMedicine
TopicHyperglycemia and glycemic control in critically ill and hospitalized patients
Canadian institutionsBentley (Canada)
Fundersnot available
KeywordsMedicineSalineInsulin aspartInsulinSodiumAnesthesiaChromatographyInternal medicineHypoglycemiaChemistry

Abstract

fetched live from OpenAlex

Aim: To investigate the stability of insulin aspartin sodium chloride 0.9% (normal saline) during storage and continuous IV infusion. Method: Five bags containing insulin 0.1 unit per mL were prepared for each of the four different experimental conditions‐room temperature, 37°C, 2 to 8°C, and within an IV administration set. Insulin was assayed by high pressure liquid chromatography. Results: The insulin concentration fluctuated for 4 hours and then remained within the prescribed range over a 24‐hour period at both room temperature and 37°C. When stored at 2 to 8°C for eight days, the concentration remained stable after one day and was always within the prescribed range. Infusion through an administration set provided a stable concentration after the initial first hour of infusion. Conclusion: Insulin aspart can be produced in batches in normal saline, stored at room temperature or 37°C for 24 hours or in the refrigerator for eight days, and administered without significant change in the prepared concentration.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.003
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.364
Threshold uncertainty score0.451

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.087
GPT teacher head0.452
Teacher spread0.365 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2004
Admission routes1
Has abstractyes

Explore more

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