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Enzyme Encapsulation by Static Mixer Method for Hydrolysis of Lactose

2012· article· en· W1543466475 on OpenAlexvenueno aff
Hui Ian Tan, Monwar Hossain, Lu Zhang

Bibliographic record

VenueInternational Journal of Biotechnology for Wellness Industries · 2012
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicProteins in Food Systems
Canadian institutionsnot available
Fundersnot available
KeywordsLactoseEncapsulation (networking)ChemistryHydrolysisEnzymatic hydrolysisEnzymeChromatographyChemical engineeringBiochemistryComputer scienceEngineering

Abstract

fetched live from OpenAlex

Enzyme immobilisation has been intensively investigated due to its advantages such as enzyme recovery, reusability and improved stability over a wide range of pH and temperatures.The encapsulation of -galactosidase incarrageenan is presented in this report for potential application in dairy industry.The immobilisation was carried out by emulsifying oil and -carrageenan with a static mixer device.This is a new approach and has the advantage of producing smaller beads (e.g.smaller than 100 m size) which can be used in continuous processing.The main factors tested were the total flow rate through the static mixer (Qt, in the range 220 -440 ml/min) and -carrageenan to oil volumetric fraction ( , in the range 0.05-0.2).The average bead sizes obtained were in the range of 19 -52 m, with smaller sizes obtained with an increase of Qt.The bead sizes decreased with (i) the decrease in emulsified droplets coalescence and oil inclusion in the beads and (ii) with the decrease in the values of WGtop (defined by the weight percentage of beads found underneath the oil layer).The bead performance was tested using lactose and 2-nitrophenyl--galactopyranoside (ONPG) and the kinetic parameters, lactose conversion and stability were determined at the optimum conditions.The attained optimum pH and temperature were 7 (similar to free enzyme) and 21 o C, respectively.The encapsulated -galactosidase tested at optimum conditions in 5% (w/v) lactose solution was able to convert 76.47% of lactose after six days.These findings contribute to the further understanding of the encapsulation technique and demonstrates the potential of usingcarrageenan as an encapsulation material for -galactosidase.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.538
Threshold uncertainty score0.325

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.027
GPT teacher head0.292
Teacher spread0.265 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2012
Admission routes1
Has abstractyes

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