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Record W1546171848

갑상선장애 환자에서 나타나는 인지기능 장애의 특징 및 관련요인

2011· article· ko· W1546171848 on OpenAlexaboutno aff
이지상, 전진숙, 변현우, 김강률, 이지웅, 최영식, 오병훈

Bibliographic record

Venue생물치료정신의학 · 2011
Typearticle
Languageko
FieldHealth Professions
TopicHealth and Wellbeing Research
Canadian institutionsnot available
Fundersnot available
KeywordsMontreal Cognitive AssessmentInternal medicineThyroidMedicineCognitionCorrelationThyroid functionTriiodothyronineEndocrinologyGastroenterologyCognitive impairmentPsychiatry
DOInot available

Abstract

fetched live from OpenAlex

Objectives:The aims of this study were to examine changes of cognitive function and its characteristics, and to identify influencing factors on cognitive fuction in patients with thyroid disorders. Methods:Data of 98 patients with thyroid disorders(16 males and 82 females) recruited from thyroid clinic in the Endocine Center of Kosin University Gospel Hospital were obtained by semi-structred interviews and MoCA-K(Korean Version of the Montreal Cognitive Assessment) and Korean version of the HDRS-17(Hamilton Depression Rating Scale-17). Results:1) The cognitive dysfunction was seen in 24 patients with thyroid disorders(24.49%). The total scores of the MoCA-K tests in thyroid patients with cognitive dysfunction(18.42±3.75) were significantly(p<0.001) lower than those of controls(26.43±2.01). Their subtest scores of the MoCA-K such as visuospatial/executive, naming, attention, language, abstraction, delayed recall were also lower than those of controls. 2) The thyroid patients with MoCA-K ≤22 showed higher age and onset age of thyroid disorders, and had lower education and HDL-cholesterol(p<0.001 respectively). 3) Total scores of the MoCA-K tests in patients with thyroid disorders had positive correlation with education(ρ=0.583, p<0.01), and had negative correlation with age(ρ=-0.462, p<0.01) and onset age of thyroid disorders(ρ=-0.494, p<0.01). Otherwise, triiodothyronine and HDL-cholesterol had positive correlation, and sex and triglyceride had negative correlation with some subtest scores of the MoCA-K. Conclusions:The cognitive dysfunction accompanied in about 1/4 of patients with thyroid disorders. The finding that the cognitive function in thyroid disorders seemed to be mainly associated with age and onset age of thyroid disorders, suggested a possibility of an important role of aging mechanism.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Science and technology studies, Research integrity, Insufficient payload (model declined to judge)
Consensus categoriesInsufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.451
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0050.001
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0020.000
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0010.004
Insufficient payload (model declined to judge)0.0330.055

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.211
GPT teacher head0.493
Teacher spread0.282 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2011
Admission routes1
Has abstractyes

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