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Record W1554377252 · doi:10.1159/000350223

Caffeine, Exercise and the Brain

2013· article· en· W1554377252 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueNestlé Nutrition Institute Workshop series · 2013
Typearticle
Languageen
FieldMedicine
TopicCoffee research and impacts
Canadian institutionsUniversity of Guelph
Fundersnot available
KeywordsCaffeineMedicineNeurosciencePsychologyPhysical medicine and rehabilitationInternal medicine

Abstract

fetched live from OpenAlex

Caffeine can improve exercise performance when it is ingested at moderate doses (3-6 mg/kg body mass). Caffeine also has an effect on the central nervous system (CNS), and it is now recognized that most of the performance-enhancing effect of caffeine is accomplished through the antagonism of the adenosine receptors, influencing the dopaminergic and other neurotransmitter systems. Adenosine and dopamine interact in the brain, and this might be one mechanism to explain how the important components of motivation (i.e. vigor, persistence and work output) and higher-order brain processes are involved in motor control. Caffeine maintains a higher dopamine concentration especially in those brain areas linked with 'attention'. Through this neurochemical interaction, caffeine improves sustained attention, vigilance, and reduces symptoms of fatigue. Other aspects that are localized in the CNS are a reduction in skeletal muscle pain and force sensation, leading to a reduction in perception of effort during exercise and therefore influencing the motivational factors to sustain effort during exercise. Because not all CNS aspects have been examined in detail, one should consider that a placebo effect may also be present. Overall, it appears that the performance-enhancing effects of caffeine reside in the brain, although more research is necessary to reveal the exact mechanisms through which the CNS effect is established.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.290
Threshold uncertainty score0.392

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.283
Teacher spread0.263 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it