Possibilities to Manage the BSE Epidemic: Cohort Culling versus Herd Culling - Experiences in Switzerland
Bibliographic record
Abstract
Bovine spongiform encephalopathy (BSE), a disease of cattle first reported in 1986 in the UK [1], has been found in the cattle populations of most European countries. To date, Japan, Israel and Canada are the only nonEuropean countries where BSE has been reported in indigenous cattle [2]. Given all available evidence, the BSE agent is not transmitted horizontally between cattle; rather it is primarily transmitted through feed. Meat-and-bone meal (MBM) is the main source of infectivity and cattle [3] are usually infected during calf-hood. Although it is likely that the other calves in a herd of a similar age to a BSE case also consumed feed from a contaminated batch of MBM, the incidence of BSE within most herds is very low. The most probable explanation is that exposure to the BSE agent was, on average, very low. Recycling of the BSE agent is likely to have resulted in an increased number of ‘packets’ of infectivity rather than an increase in the average titre of infectivity within a contaminated batch of MBM. As a result, the average within-herd incidence would be unlikely to increase [4] (see also the chapter of Bradley). Several strategies, including those that focus on feed as a source of infection and various culling programmes, have been adopted with the aim of eradicating BSE. Culling strategies vary from culling the affected animal only, to culling all animals within the birth cohort of the BSE case, to culling the entire herd.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".