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Prebiotic Fiber Consumption Decreases Energy Intake in Overweight and Obese Children

2015· article· en· W1574716891 on OpenAlexafffundabout
Megan Hume, Alissa C. Nicolucci, Raylene A. Reimer

Bibliographic record

VenueThe FASEB Journal · 2015
Typearticle
Languageen
FieldMedicine
TopicObesity, Physical Activity, Diet
Canadian institutionsUniversity of Calgary
FundersCanadian Institutes of Health Research
KeywordsOverweightPrebioticMedicineAppetiteObesityPopulationProspective cohort studyPlaceboPhysiologyFood scienceAnimal scienceInternal medicineEnvironmental healthBiology

Abstract

fetched live from OpenAlex

Excess energy intake is thought to be a major driver of the obesity epidemic and even small disturbances in energy balance may lead to the onset of pediatric obesity. Prebiotic fiber improves appetite regulation and decreases energy intake in obese adults; however, its' therapeutic potential in the obese pediatric population has not been investigated. To determine the effect of prebiotic fiber intake on prospective food consumption and energy intake in the obese pediatric population, 39 male and female overweight and obese children (7‐12y) consumed 1) 8 g/d of prebiotic fiber (1:1 oligofructose:inulin); or 2) equicaloric dose of maltodextrin for 16 wk. Subjective appetite ratings were obtained before and after an ad libitum breakfast buffet at 0 and 16 wk as well as Children's Eating Behaviour Questionnaire (CEBQ) scores. Energy intake was measured at the breakfast buffet and in weighed 3‐day food records. The first of 2 cohorts to complete the study showed a decreased desire to eat following fiber supplementation (p=0.02). There was also a trend for increased fullness and decreased prospective food consumption in the fiber group. CEBQ scores showed increased satiety responsiveness with fiber consumption (p=0.01). The change in energy intake at the final breakfast buffet was 84 kcal lower with fiber versus placebo. In conclusion, long term prebiotic fiber intake may lead to reductions in energy intake that positively impact body weight. Potential causes for decreased energy intake include heightened satiety responsiveness and fullness following fiber consumption. Funded by CIHR, BMO Financial Group,Alberta Children's Hospital Research Institute.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.010
Threshold uncertainty score0.314

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.023
GPT teacher head0.260
Teacher spread0.237 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations7
Published2015
Admission routes3
Has abstractyes

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