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Record W1577414990 · doi:10.15537/1658-3175.3558

Giant cell tumor of the rib

2006· article· en· W1577414990 on OpenAlex
Mohammed Lafi Al-Otaibi, Fawzi Aljassir, Marc Isler

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueSaudi Medical Journal · 2006
Typearticle
Languageen
FieldMedicine
TopicBone Tumor Diagnosis and Treatments
Canadian institutionsUniversité de MontréalMcGill University
Fundersnot available
KeywordsMedicineRib cageRadiologyAnatomyFibrous dysplasiaCalcificationRadiographySarcomaSurgeryPathology

Abstract

fetched live from OpenAlex

G cell tumor (GCT) accounts for approximately 15% of symptomatic benign bone tumors. These locally aggressive lesions may, in less than 5% of cases, be associated with lung metastases.1 They occur more often in females than in males, and usually affect patients in the third and fourth decades of life. Approximately 75% are found in the epiphyses of long bones, most commonly the distal femur and proximal tibia. These 2 sites account for more than 50% of all cases. Other locations include the distal radius, proximal humerus, vertebrae, and sacrum. The rib is the least common site.2 We report a rare case of painless GCT of the rib. A 46-year-old Caucasian female presented with a one-year history of painless swelling in the left side of the anterior chest wall. There was no history of trauma, and no constitutional symptoms. Physical examination revealed a firm, non-tender, non-pulsatile 8 x 5 cm mass in the mid-axillary line of the left chest wall with overlying normal skin. Plain radiographs showed an expansile lytic lesion with areas of sclerosis in the anterior aspect of left 9th rib. A CT scan without contrast showed a large expansile mass with enhancing margins and internal septae with evidence of calcification involving the anterior aspect of the left ninth rib. At this point, the differential diagnosis included fibrous dysplasia, aneurysmal bone cyst, Ewing’s sarcoma, lymphoma, and chondrosarcoma.3 She underwent core needle biopsy, which revealed GCT. Surgery was planned. With the patient positioned in lateral decubitus and under general anesthesia, en bloc resection of the 9th rib was performed with a wide margin (Figure 1). A chest tube was inserted at the time of closure and removed on the 2nd postoperative day. The surgical specimen measured 9.5 cm x 6.5 cm x 3 cm. On histological examination, there were large numbers of multinucleate giant cells separated by mononuclear stromal cells, consistent with the diagnosis of GCT. She made an uneventful recovery, and was discharged home on the 3rd post operative day. She remains free of disease. Giant cell tumor of bone occurs infrequently, arising primarily in the ends of long bones. The chest wall represents a rare site for such pathology; however, GCT should be kept in mind when evaluating a rib lesion.4 The principles of oncology should be followed and include proper axial imagery as well as needle or incisional biopsy, carefully placed and executed so as not to interfere with definitive treatment. Since the rib is considered an ‘expendable’ bone, and marginal or wide resection presents significantly less risk of recurrence than intralesional excision (curettage), such treatment seems preferable and is associated with few complications in this site.5

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.160
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.007
GPT teacher head0.239
Teacher spread0.233 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it