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Record W1594857509 · doi:10.1002/0471440264.pst610

Self‐Immolative Polymers

2015· other· en· W1594857509 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueEncyclopedia of Polymer Science and Technology · 2015
Typeother
Languageen
FieldMaterials Science
TopicDendrimers and Hyperbranched Polymers
Canadian institutionsWestern University
Fundersnot available
KeywordsDepolymerizationMoietyChemistryPolymerCleavage (geology)MicelleNanotechnologyCombinatorial chemistryPolymer chemistryOrganic chemistryMaterials scienceAqueous solution

Abstract

fetched live from OpenAlex

Self‐immolative linear polymers are a recently developed class of materials that typically undergo head‐to‐tail depolymerization in response to the cleavage of stimuli‐responsive end‐caps from their termini. These polymers have been inspired by self‐immolative dendrimers and oligomers that undergo cascades of cyclization and/or elimination reactions in response to the activation or cleavage of a trigger moiety. During the past decade, several backbones have been introduced including polycarbamates, polycarbonates, polythiocarbamates, polythiocarbonates, polyacetals, and poly(benzyl ether)s. These backbones have been tuned to control the depolymerization rate, and end‐caps responsive to stimuli including enzymes, light, heat, acid, and small molecules such as fluoride ions have been incorporated. They have been explored for the development of sensing devices, microcapsules, and nanoscale assemblies such as micelles and vesicles. In these applications, their depolymerization in response to end‐cap cleavage affords effective amplification of these stimuli, resulting in enhanced sensitivity. Their depolymerization kinetics has also been studied in detail. This article will review the development and current status of both the chemistry and application of linear self‐immolative polymers.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Science and technology studies, Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Other · Consensus signal: Other
Teacher disagreement score0.134
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0020.002
Science and technology studies0.0000.004
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.006
GPT teacher head0.235
Teacher spread0.229 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it