Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
Abstract The chapter provides a comprehensive review of the current knowledge concerning the anatomical, physiological, and neurochemical substrates that underlie both physiological and pathological pain. Thus, we describe in detail the pathways that underlie the transmission of inputs from the periphery to the CNS, the physiological properties of the neurons activated by painful stimuli, and the neurochemicals that mediate or modulate synaptic transmission in somatosensory pathways. A special effort has been made to identify critical advances in the field of pain research that point to the processes by which pathological pain develops following tissue or nerve injury, as well as how pain is modulated by various brain mechanisms. The review of the peripheral nervous system concentrates on differences in the properties of the primary afferent neurons that transduce and relay painful messages to the CNS, and how their responses are affected by injuries that produce inflammation. The review of spinal cord dorsal horn concentrates on what is known about the neurochemical influences on synaptic transmission, and how they are affected by inflammatory and nerve injuries in the periphery. The review of pain processing in the brain focuses on the role of various brain regions in the determination of the multidimensional nature of pain, as discerned by anatomical connectivity, physiological function, and brain imaging. Finally, insights are provided into the future of pain research, with a focus on molecular biology, and behavioral genetics as a means to understand individual differences in pain sensitivity and expression.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.000 |
| Insufficient payload (model declined to judge) | 0.003 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it