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Record W164082874

The proteome analyst suite of automated function prediction tools

2005· article· en· W164082874 on OpenAlexaff
Brett Poulin, Duane Szafron, P. Lu, Russell Greiner, David S. Wishart, Roman Eisner, Alona Fyshe, Brandon Pearcy, Luca Pireddu

Bibliographic record

VenueNational Conference on Artificial Intelligence · 2005
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicMachine Learning in Bioinformatics
Canadian institutionsUniversity of Alberta
Fundersnot available
KeywordsProteomeGene ontologyComputer scienceFunction (biology)SuiteOntologySequence (biology)Computational biologySubcellular localizationData miningBioinformaticsGeneBiologyBiochemistryGenetics
DOInot available

Abstract

fetched live from OpenAlex

Proteome Analyst (PA) is a publicly available, high-throughput, web-based system for automatically predicting the function and properties of proteins. Biologists can use PA to predict, for example, the Gene Ontology (GO) molecular function and subcellular localization of a protein based on sequence information. Using sequence analysis tools and machine learning, PA gives high accuracy and broad coverage for both molecular function and subcellular localization predictions.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.010
Threshold uncertainty score0.033

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.004
Meta-epidemiology (narrow)0.0030.001
Meta-epidemiology (broad)0.0020.002
Bibliometrics0.0050.003
Science and technology studies0.0010.000
Scholarly communication0.0020.002
Open science0.0030.002
Research integrity0.0010.003
Insufficient payload (model declined to judge)0.0100.016

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.056
GPT teacher head0.333
Teacher spread0.277 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2005
Admission routes1
Has abstractyes

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