The Effect of Sn(IV) Chlorin e6 on HepG2 Cancer Cell Lines
Bibliographic record
Abstract
This research investigated the effect of Sn(IV) chlorin e6 dichloride trisodium salt photosensitizer on the viability of HepG2 cancer cell lines in vitro. The effect of light on the viability of cells without the photosensitiser and the toxicity of the photosensitiser in the absence of light were examined in this research. No toxic effects with the absence of light were found and no photodamge effect on the cells without the presence of photosensitiser. The effect of different concentrations of the photosensitiser with fixed light dose of 70 J/cm2 on the viability of HepG2 cancer cells were performed. Then, two concentrations 25 and 30 μg/ml were investigated at different light doses 60-100 J/cm2. The effect of the photosensitiser on the viability of HepG2 at different light doses and different concentrations was found to have low viability over concentrations of 25 μg/ml. This could be due to that the photosensitiser reached a saturated status after this concentration. Key words: PDT; Sn(IV) chlorin e6; liver cancer; phototoxicity; viability assay
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".