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Record W1719823452 · doi:10.1155/2013/514130

Something Old, Something New, Something Borrowed…

2013· article· en· W1719823452 on OpenAlexaff
Louis Valiquette, Kevin B. Laupland

Bibliographic record

VenueCanadian Journal of Infectious Diseases and Medical Microbiology · 2013
Typearticle
Languageen
FieldMedicine
TopicClostridium difficile and Clostridium perfringens research
Canadian institutionsRoyal Inland HospitalUniversity of CalgaryUniversité de Sherbrooke
Fundersnot available
KeywordsClostridium difficilePseudomembranous colitisDiarrheaMedicineFecal bacteriotherapyFecesIntensive care medicineGastroenterologyMicrobiologyBiology

Abstract

fetched live from OpenAlex

Although knowledge of the complex interactions within our intestinal microbiota is relatively new, fecal microbiota transplantation (FMT) has been practiced for a long time. For more than a millennium, human fecal suspensions have been used to treat various ailments. The first literary evidence of oral fecal administration for the treatment of food poisoning and diarrhea dates back to the fourth century in China as detailed in the first Chinese handbook of emergency medicine written by Ge Hong (1). Later, in the 16th century, Li Shizhen described the use of several different human stool preparations for the treatment of various gastrointestinal diseases (1). The first report of FMT for the treatment of pseudomembranous colitis dates back to 1958 (2). In this case series involving four patients, all responded spectacularly. In 1983, Schwan et al (3) published the first report of FMT in a patient with a confirmed Clostridium difficile infection (CDI). Since then, the experiences of more than 250 CDI patients treated with FMT has been published in the medical literature, with an overall success rate of approximately 90% (4,5)...

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.008
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.023
Threshold uncertainty score0.078

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.008
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.001
Science and technology studies0.0030.008
Scholarly communication0.0080.012
Open science0.0010.003
Research integrity0.0030.008
Insufficient payload (model declined to judge)0.0230.012

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.262
Teacher spread0.251 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2013
Admission routes1
Has abstractyes

Explore more

Same venueCanadian Journal of Infectious Diseases and Medical Microbiology→Same topicClostridium difficile and Clostridium perfringens research→French-language works237,207→