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Risks of nutritional deficiencies in young adult type 1 diabetic (T1D) women

2009· article· en· W1743455968 on OpenAlexaff
Priscille G. Massé, Belinda Elisha, Carole C. Tranchant, Karen L. Ericson, Sharon M. Donovan, Rodney Ouellet

Bibliographic record

VenueThe FASEB Journal · 2009
Typearticle
Languageen
FieldMedicine
TopicFolate and B Vitamins Research
Canadian institutionsDr. Georges-L.-Dumont University Hospital CentreUniversité de Moncton
Fundersnot available
KeywordsInternal medicineEndocrinologyAlkaline phosphataseFerritinMedicineIron deficiencyVitaminTransferrinType 1 diabetesAlbuminPyridoxalDiabetes mellitusBiologyAnemiaPhosphateBiochemistryEnzyme

Abstract

fetched live from OpenAlex

Although nutrition plays a crucial role in the treatment of T1D, there are few studies on the nutritional status. This study aimed to evaluate a target group at risk of nutritional deficiencies. Women with well‐controlled T1D and without renal complications (n=22) and healthy controls (n=27), aged 30‐40 yr‐old, were rigorously selected, having normal body weight and being not pregnant nor vegetarian, among other selection criteria. The two groups were comparable in many aspects. T1D, diagnosed since 21 yrs in average, was monitored by HbA1c level. Serum transferrin ( P<0.02 ) and IGF‐1 concentrations ( P<0.001 ) were reduced in the T1D group. There was no significant difference for albumin. Serum iron concentration was also reduced ( P<0.03 ), although body stores (ferritin) were not affected. Contrarily to other studies, serum Mg and plasma pyridoxal phosphate (PLP, vitamin B6 coenzyme) were not reduced, although alkaline phosphatase, which regulates the concentration of this vitamin, was increased ( P<0.01) . Plasma PLP was below reference value. Erythrocyte folate was greater ( P<0.03 ) in TID group due to a greater number of subjects taking supplements and more control subjects with values in the low range. This study evidenced T1D‐induced metabolic changes in regard to protein and iron status. It also showed a risk of deficiency for vitamin B6.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.006

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.048
GPT teacher head0.331
Teacher spread0.283 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2009
Admission routes1
Has abstractyes

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