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Record W177644485 · doi:10.1096/fasebj.21.5.a575-b

Sprint versus endurance training: Metabolic adaptations in working human skeletal muscle

2007· article· en· W177644485 on OpenAlexaffabout
Kirsten A. Burgomaster, Krista R. Howarth, Stuart M. Phillips, Mark Rakobowchuk, Maureen J. MacDonald, Martin J. Gibala

Bibliographic record

VenueThe FASEB Journal · 2007
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicMuscle metabolism and nutrition
Canadian institutionsMcMaster University
Fundersnot available
KeywordsSprintEndurance trainingCitrate synthaseInterval trainingGlycogenolysisSkeletal musclePhosphocreatineInternal medicineMedicineCyclingEndocrinologyVO2 maxAnimal sciencePhysical therapyHeart rateEnergy metabolismGlycogenChemistryBiologyBiochemistry

Abstract

fetched live from OpenAlex

BACKGROUND: Brief, intense exercise training induces metabolic adaptations in working human skeletal muscle that are comparable to traditional endurance training (Burgomaster, J Appl Physiol 100 : –2047, 2006). However, no study has directly compared the metabolic adaptations to these diverse training strategies in a standardized manner. PURPOSE: We examined changes in skeletal muscle metabolism during a fixed bout of exercise (1 h cycling at 65% of pre‐training VO2peak) before and after 6 wks of either low volume sprint‐interval training (SIT) or high volume endurance training (ET). Twenty subjects (23±1 yr, VO 2 peak = 41±1 ml/kg/min) were assigned in a counterbalanced manner to a SIT or ET group (n=5 men and 5 women per group). Subjects performed either SIT (4–6 repeats of 30 s “all out” cycling at ~250% VO2peak with 4.5 min recovery per d, 3 d/wk) or ET (40–60 min of continuous cycling at ~65% VO2peak per d, 5 d/wk). Weekly training time commitment was ~1 h for SIT and ~4.5 h for ET, and total training volume was ~80% lower for SIT versus ET (~630 vs ~3000 kJ per wk). Training increased VO2peak and the maximal activity of citrate synthase and 3‐hydroxyacyl‐CoA dehydrogenase with no difference between groups (main effects, P<0.05). Similarly, training decreased net muscle glycogenolysis, phosphocreatine degradation and lactate accumulation but there was no difference between groups (main effects, P<0.05). CONCLUSION: Given the large difference in training volume, these data demonstrate that SIT is a time efficient strategy to induce skeletal muscle metabolic adaptations during exercise that are comparable to ET in young men and women. Supported by NSERC Canada and an ACSM Doctoral Research Grant (KAB)

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.010

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.048
GPT teacher head0.290
Teacher spread0.242 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2007
Admission routes2
Has abstractyes

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