Differential transcriptome analyses of three wheat genotypes reveal different host response pathways associated with Fusarium head blight and trichothecene resistance
Why this work is in the frame
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Bibliographic record
Abstract
Fusarium head blight is a disease of cereal crops caused by a group of trichothecene‐producing Fusarium species. In the current study, three wheat genotypes with cv. Superb pedigree were evaluated for their ability to activate different defence‐response pathways when exposed to one of three elicitors: (i) trichothecene‐producing and (ii) non‐producing F. graminearum strains, and (iii) the trichothecene toxin deoxynivalenol. Spikelets distal to the inoculation point were harvested at multiple time points in order to identify systemic temporal changes in transcript accumulation associated with resistance. Distinct differences were observed between the resistant genotypes and cv. Superb, as well as between the two resistant genotypes. The current data suggest that different molecular mechanisms exist not only between susceptibility and resistance responses, but between different forms of genetic resistance. It is proposed that Type 1 resistance in one of the resistant double haploid lines evaluated here involves a combination of structural features that slow fungal penetration and activation of a systemic response in uninfected tissues adjacent to the site of infection to prevent or minimize secondary infection; in contrast, Type 2 resistance is more likely a form of local resistance.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it