The Efficacy of Meloxicam Oral Suspension for Controlling Pain and Inflammation After Castration in Horses
Why this work is in the frame
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Bibliographic record
Abstract
The objective of the study was to evaluate the efficacy of a meloxicam oral suspension (MOS) for pain and inflammation control after castration in horses. The study consisted of 88 healthy, unbroken, 2-year-old mixed breed horses (primarily Quarter horse and draft type). Group 1 animals (n = 44) received MOS at the dose of 0.6 mg per kg body weight administered orally at the time of castration then daily for two consecutive days. Group 2 animals (n = 44) received 0.9% saline at the dose of 1 mL per 25-kg body weight administered orally at the time of castration then daily for two consecutive days. Animals were castrated on day 0 and observed for clinical signs of pain and inflammation for four (4) consecutive days. Pain behavior scores and visual analog scores were significantly greater in control animals over meloxicam-treated animals at all observation periods (P < .05). The Stiffness Score at the time of leaving the chute was significantly different in control animals over meloxicam-treated animals at all observation periods (P < .05). The meloxicam-treated animals had significantly greater movement indices 24 to 96 hours after castration (P < .05). Meloxicam-treated animals had significantly lower swelling than control animals at all observation periods (day 1, day 2, and day 3; P < .05). It is concluded that daily administration of MOS at a dose of 0.6 mg/kg for 3 days significantly reduces postsurgical pain and inflammation in horses for at least 4 days after castration.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.013 | 0.008 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.001 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it