MétaCan
Menu
Back to cohort
Record W1837091423 · doi:10.7322/jhgd.50414

IMPACT OF BIRTH-WEIGHT ON ADULT MINOR ILLNESS

2013· article· en· W1837091423 on OpenAlex
Amit Mukerji, Jaques Belik

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueJournal of Human Growth and Development · 2013
Typearticle
Languageen
FieldMedicine
TopicBirth, Development, and Health
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsMinor (academic)PsychologyLow birth weightPediatricsMedicinePregnancyArtHumanitiesBiology

Abstract

fetched live from OpenAlex

There is now well-established evidence that low birthweight has important health implications beyond infancy and childhood as suggested by the fetal origins of disease theory1. It postulates that in utero under-nutrition leads to permanent changes to the physiology and metabolism of the body, in part explaining the higher incidence of cardiovascular illnesses,2,3 stroke,4 and type 2 diabetes5 in that population. In addition, lower birthweight is associated with higher mortality rates from all causes6 . An area where the evidence is still in early stages is that of the link between birthweight and adult minor illnesses. These conditions include common cold and viral respiratory tract infections, headache and gastrointestinal disturbances and account for between 18-40% of the general practitioner’s time7,8. Minor illnesses also have significant economic impact. They were estimated to cost the UK’s National Health Service (NHS) $2.2 billion per year7 and lead to significant workabsenteeism9 . Such disease-related economic impact led not only to an emphasis on promoting self-care measures for minor ailments,10 but also an attempt to better understand its epidemiology. Previous work by Belingham-Young11 introduced the notion that birthweight may be related to adult minor illness. Until now, such notion only garnered limited attention and the current study by the same group filled this important knowledge gap12. In this cross-sectional retrospective cohort study, the authors used a minor illness checklist completed by 258 participants (219 female, 39 male) who identify themselves as having been born at term and knew their birthweight. A median split of the total scores was used to divide the participants into low and high minor illness groups. They were also grouped based on optimal (3,500 – 4,500 grams) and suboptimal birthweight (2540 – 3490 grams). Interestingly, minor illness scores were significantly lower for those in the optimal birthweight, and there was a significant negative correlation between birthweight and minor illness score. The authors argue that their findings have significant public health implications. Health care prevention initiatives favoring individuals of suboptimal birth weights may have a positive impact on the frequency and severity of minor infection-related illnesses. As suggested by the authors, targeting influenza vaccinations towards this high risk group may be cost-effective in terms of preventing complications associated with this infection. However, they also address some of the practical challenges of broad implementation of health policies based on birthweight, as such data is often limited to the patients’ chart. An Equilibrium Model is discussed that may help public health practitioners in identifying and prioritizing local implementation. The results of this study bear particular public health importance as there is tremendous focus on curbing rising health care costs, especially as many parts of the world are faced with an increasingly aging population13. Yet, there are a few points worth considering. Although in part Journal of Human Growth and Development 2013; 23(1): 7-10 EDITORIAL

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.045
Threshold uncertainty score0.509

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.289
Teacher spread0.271 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it