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Record W1857955060

Acute ‘Olympic’ Hepatitis: A Medical Experience from the Vancouver 2010 Games

2011· article· en· W1857955060 on OpenAlexaffvenueabout
Pamela Verma

Bibliographic record

VenueUBC Faculty of Medicine medical journal · 2011
Typearticle
Languageen
FieldMedicine
TopicHepatitis Viruses Studies and Epidemiology
Canadian institutionsUniversity of British Columbia
Fundersnot available
KeywordsMedicineSerologyHepatitis AHepatitisLiver biopsyHepatitis BLiver functionHepatitis EInternal medicineHepatitis E virusPast medical historyPediatricsBiopsyImmunologyAntibody
DOInot available

Abstract

fetched live from OpenAlex

A visitor from Asia, visiting for the Opening Ceremonies of the 2010 Vancouver Olympic Games, who was in his mid 50s, was referred to the on-call Olympic Gastroenterology Specialist Group with acute hepatitis. The patient had no previous history of alcoholism or Hepatitis B or C infection. On presentation, he was found deeply jaundiced without any clinical encephalopathy and stigmata of chronic liver disease . Initial laboratory investigations revealed acute liver failure which was complicated by renal impairment. He was admitted to the Vancouver General Hospital. His immediate prognosis was considered significant enough to result in referral to the liver transplant services. With increasing global travel to Vancouver, it is apparent that acute HEV will need to be considered in the differential diagnosis of any patient with acute liver failure. Appropriate screening tests included Hepatitis A, B and C viral serology, metabolic and autoimmune markers, which were all negative. The initial history suggested hepatotoxicity from Traditional Chinese Medicines; however after a careful review via an interpreter, it was clear that the herbal medications were consumed after the patient became ill. A liver biopsy was performed which revealed features consistent with acute Hepatitis E (HEV). Subsequent positive viral serology for anti-HEV IgM then positive confirmed a diagnosis of acute HEV. After clinical review of the incubation time of acute HEV and the timeline of the patient’s visit to Vancouver, it was apparent that the infection was acquired in Asia. The patient’s liver function improved with conservative treatment and he was able to return home.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.013
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Science and technology studies, Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.417
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.013
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.003
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.002
Insufficient payload (model declined to judge)0.0350.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.074
GPT teacher head0.348
Teacher spread0.274 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2011
Admission routes3
Has abstractyes

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