Circadian Organization of the Neuroendocrine System of an Adult Insect, Rhodnius Prolixus (STÄL) (HEMIPTERA)
Bibliographic record
Abstract
Circadian clocks synchronize with external environmental cycles and regulate rhythms throughout the organism, creating an internal temporal organization of cellular and physiological processes. In the model insect Rhodnius prolixus the prothoracicotropic hormone (PTTH)-ecdysteroid axis is a central component of the larval circadian system. However, PTTH is considered a larval hormone and its only known target, the ecdysteroid-producing prothoracic glands, are absent in adults. Here, PTTH is demonstrated to be present in adult female Rhodnius and its synthesis and release during the period of egg development and oviposition were shown to fluctuate with a daily rhythm that is controlled by the circadian clock in the brain. Ecdysteroids are also present during this time and their levels in hemolymph and ovaries undergo synchronous daily variations that are likewise under clock control. Ovaries are the only adult tissue examined that both contained and released ecdysteroids. It is inferred that the ovaries generate the rhythm of ecdysteroids in the hemolymph. The parallel patterns of PTTH and ecdysteroid release suggest these processes are related and it is tempting to speculate that the PTTH-ecdysteroid axis persists in the adult leading to the orchestration of complex adult-specific processes, such as egg development and oviposition.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".