Case 2: Long-standing neuropathy with acute onset of weakness
Bibliographic record
Abstract
A 16-year-old girl with presumed Charcot-Marie-Tooth disease presented to the emergency department with an acute onset of lower limb weakness. She was unable to walk where previously she had been fully ambulatory. One month before presentation, she had a three-week history of abdominal pain. Five days before presentation, she developed bilateral shoulder and upper back pain. The morning of her presentation, she had difficulty getting up off the floor and getting in and out of the bathtub. She reported that her legs were numb and ‘wobbly’. She had no presyncopal symptoms. She denied urinary incontinence. Bowel dysfunction was difficult to assess because she usually stooled once per week. She had no fevers or night sweats. Her history was significant for orthopaedic surgeries. She was followed for bilateral pes cavus deformities and progressive right foot varus deformity for which she had required surgery several years earlier. Her presumed diagnosis of Charcot-Marie-Tooth disease was based on her orthopaedic findings and her family history. Her mother, maternal aunt and other relatives on her mother's side had been diagnosed by genetic testing. The patient herself had not had genetic testing and was not followed by a neurologist at the time of presentation. As a result, her premorbid neurological examination was unknown.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.005 |
| Meta-epidemiology (narrow) | 0.003 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.003 | 0.001 |
| Scholarly communication | 0.002 | 0.003 |
| Open science | 0.002 | 0.002 |
| Research integrity | 0.006 | 0.003 |
| Insufficient payload (model declined to judge) | 0.004 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".