<i>EX VIVO</i>EQUINE HEART AND LUNG PERFUSION SYSTEM
Bibliographic record
Abstract
An ex vivo heart lung perfusion system (EVHLPS) was designed and constructed in order to facilitate the study of hemodynamic and mechanical phenomena associated with the equine pulmonary vascular system. Fresh en bloc heart and lung preparations collected from adult horses were placed in an enclosed chamber in normal anatomic orientation and perfused with isotonic phosphate buffered saline (PBS) via a closed loop, pulsatile perfusion system. Pulmonary artery (PA) pressure, left atrial pressure and perfusate temperature were regulated. Lungs were ventilated by static lung inflation and dynamic positive pressure ventilation (PPV). Instrumentation was introduced into the pulmonary arterial system via an instrument chamber incorporated in the perfusate flow piping upstream from the cranial vena cava. Key physiologic parameters (mean [SD]); PA flow (1.57 [0.61] L/min); systolic pressure (SAP) (42.5 [6.83] mmHg); diastolic pressure (DAP) (30.3 [3.86] mmHg); and perfusate temperature (37.1 [0.46]°C) were observed with en bloc heart and lung preparations (n = 5). PA pulse wave velocity (PWV) was found to vary from 1.72 to 12.50 m/s (n = 2) and appeared to have directly proportional relationships with mean arterial pressure (MAP) and distance within the PA.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.004 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".