Invertebrate Neuropeptide Conference
Bibliographic record
Abstract
Juvenile hormone plays a central role in the metamorphosis and reproduction of most insect species.The biosynthesis of juvenile hormone within the corpora allata of insects is regulated by neuropeptides.Allatostatin neuropeptides are known to act as inhibitors of juvenile hormone biosynthesis Allatotropin may, in certain insects, act to stimulate JH biosynthesis.These neuropeptides act on a membrane receptor(s) of the corpora allata that activates signal transduction pathway(s).This activation ultimately serves to regulate enzymes in the biosynthetic pathway that converts acetyl CoA to the sesquiterpenoids.Farnesoic acid o-methyltransferase (FAMeT) catalyzes the S-adenosylmethionine dependent conversion of Farnesoic acid to methylfarnesoic acid.It is thought that FAMeT may play a rate-limiting role in juvenile hormone biosynthesis in insects.FAMeT has been identified in the crustaceans, Metapenaeus ensis (shrimp) and Homarus americanus (Lobster).A database search based on sequence identity with crustacean FAMeT has revealed a putative gene product in Drosophila melanogaster.In order to characterize the putative Drosophila FAMeT ortholog's role in juvenile hormone biosynthesis we have analyzed the protein distribution, activity and in vivo expression.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.020 | 0.011 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".