An Investigation of Impulsivity in Children With Early-Treated Congenital Hypothyroidism
Bibliographic record
Abstract
The main feature of congenital hypothyroidism (CH) is a total or partial absence of thyroid hormone, caused by a developmental disorder of the thyroid gland. Introduction of neonatal thyroid screening allows early treatment with replacement hormone. As a result the prognosis of CH has greatly improved but neuropsychological problems do still occur. Claims that early-treated CH is associated with impulsivity were tested with a memory search task comprising 2 response probability conditions: a baseline condition in which "yes" and "no" responses were equally probable and a response bias condition in which the probability of a "no" response was raised to 70%. Impulsivity was defined as the ability to stop and change a response set and was assessed from the amount of inaccurate "no" responses made. Comparisons were made between 47 children with early-treated CH and 35 controls at the age of 7.5 years. Children with early-treated CH were notably slow and variable in their overall task performance but, most important, did not show signs of poor impulse control. Suggested short-term memory problems in these children could not be confirmed. Performance could not be attributed to early disease-related factors or lowered intelligence.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.003 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.002 | 0.001 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".