Effect of Lung Inflation on Ventilation and Various Phases of the Respiratory Cycle in Preterm Infants
Bibliographic record
Abstract
The effect of sudden and sustained lung inflation on inspiratory time (Ti), expiratory time (Te) and duration of apnea, as a translation of the Hering-Breuer reflex, has not been systematically analyzed in preterm infants. To examine such effects, 10 infants (body weight 1,550 +/- 110 g; gestational age 31 +/- 1 weeks) were studied. Lung inflation was obtained by applying negative pressure around the chest using a negative pressure incubator. After a control period, lung volume functional residual capacity was increased by an average of 14, 23, 34 and 53%. During lung inflation, Ti, Te, total respiratory cycle duration, incidence and duration of apnea increased. Minute ventilation decreased due to a decrease in frequency. Tidal volume decreased but not significantly. Inspiratory and expiratory flows decreased. These results (1) confirm the presence of the Hering-Breuer reflex in preterm infants, as reflected by increased Te and appearance of apnea during lung inflation; and (2) show that contrary to expectations, Ti increased significantly with lung inflation.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".