Current status of autologous bone marrow cell infusion therapy for liver cirrhosis patients
Bibliographic record
Abstract
This article reviews recent translational research on the development of cell therapy using autologous bone marrow cell for liver cirrhosis patients. A clinical study of autologous bone marrow cell infusion (ABMI) therapy for liver cirrhosis patient was begun on Nov. 14, 2003. We previously reported nine liver cirrhosis (LC) cases that underwent ABMI from the peripheral vein and followed their progress up to 24 weeks. Subjects were LC patients with total bilirubin TB of < 3.0 mg/dL, platelets > 5 (10(10)/L) and no viable hepatocellular carcinoma on diagnostic imaging. Mononuclear cells (MNCs) were separated by cell washing and were infused via the peripheral vein. After ABMI therapy liver function and Child-Pugh Score were significantly improved at 4 weeks and 24 weeks (P < 0.05). A total of 23 cases of ABMI therapy have been performed for LC patients to date. No major adverse effects were noted due to ABMI therapy. In conclusion, ABMI therapy should be considered as a novel treatment for LC patients.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".