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Record W1967342028 · doi:10.4212/cjhp.v64i6.1091

Fludrocortisone for Heparin-Induced Hyperkalemia

2011· article· en· W1967342028 on OpenAlexaffvenue
Glen Brown

Bibliographic record

VenueThe Canadian Journal of Hospital Pharmacy · 2011
Typearticle
Languageen
FieldMedicine
TopicPotassium and Related Disorders
Canadian institutionsSt. Paul's Hospital
Fundersnot available
KeywordsFludrocortisoneHyperkalemiaHeparinMedicineInternal medicineHydrocortisone

Abstract

fetched live from OpenAlex

Fludrocortisone for Heparin-Induced HyperkalemiaHeparin, which continues to be used widely for prophylaxis and treatment of thromboembolism, is associated with a risk of hyperkalemia. 1 Clinicians should be aware of strategies to address heparin-induced hyperkalemia.The following account supports the utility of fludrocortisone in normalizing renal processing of potassium during heparin therapy.A patient* was transferred from a peripheral community hospital for syncope associated with complete heart block (heart rate 39-45/min).On the evening of admission, intubation and mechanical ventilation were required for hypercapnic respiratory failure.A permanent pacemaker was inserted the next morning, which increased the patient's heart rate and improved signs of perfusion to the vital organs (kidney, brain, and skin).Elevated serum creatinine at the time of admission was thought to be a sign of impaired renal perfusion secondary to the heart block.Given the patient's body habitus, weaning from mechanical ventilation was prolonged, but extubation to biphasic positive airway pressure (BiPAP) via a face mask was successful on day 12 of the admission.During the weaning process, renal function improved, as indicated by declining concentrations of serum creatinine (Figure 1).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.005
Threshold uncertainty score0.014

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.053
GPT teacher head0.286
Teacher spread0.233 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations9
Published2011
Admission routes2
Has abstractyes

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Same venueThe Canadian Journal of Hospital PharmacySame topicPotassium and Related DisordersFrench-language works237,207