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ABSORBED DOSE TO THE ADULT MALE AND FEMALE BRAIN FROM 18F-FLUORODEOXYGLUCOSE

2001· article· en· W1967784864 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueHealth Physics · 2001
Typearticle
Languageen
FieldMedicine
TopicMedical Imaging Techniques and Applications
Canadian institutionsMcMaster University Medical Centre
Fundersnot available
KeywordsFluorodeoxyglucoseMedicineNuclear medicineAdult malePhysiologyPositron emission tomographyInternal medicine

Abstract

fetched live from OpenAlex

The absorbed doses to adult male and female brains from 18F-fluorodeoxyglucose were investigated. A total of eight male and six female patients undergoing clinical positron tomography brain scans were included in this study. This patient population allowed for a comparison of the absorbed dose to the brain in men and women. For each patient, time-activity curves for the brain were generated, yielding cumulated activity measurements for the entire organ. From these cumulated activities the average residence times for both male and female subjects were calculated and then multiplied by the S-values from the MIRDOSE 3.1 software program for absorbed dose estimates. The average absorbed dose per administered activity to the adult male brain was found to be 4.2 x 10(-2) mGy MBq(-1), which is lower than that found for the adult female brain of 5.3 x 10(-2) mGy MBq(-1). Six of the male and all six female subjects were each studied on two separate occasions, allowing for an analysis of within-subject variability. The average variation in the self-dose for all 12 patients was found to be within 14%, suggesting that in most cases this method of obtaining a single dose estimate is precise.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.364
Threshold uncertainty score0.299

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.039
GPT teacher head0.363
Teacher spread0.325 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it