P1.15 ASSESSING THE CORRELATES OF ARTERIAL STRUCTURE AND FUNCTION IN HEALTHY ADOLESCENTS
Bibliographic record
Abstract
Introduction: Chronic obstructive pulmonary disease (COPD) is a systemic disease associated with impaired cardiac function.A reduction in stroke volume and cardiac output can be present even with normal ejection fraction in these patients.The non-invasive cardiac output measurement (NICOM) is a simple tool to measure stroke volume (SV) and cardiac output (CO).The aim of this study is to examine the reproducibility of the NICOM in patients with COPD.Method: The Assessment of Risk in Chronic Airways Disease Evaluation (ARCADE) is a longitudinal study of up to 1500 patients with COPD confirmed with spirometry.Thirty patients with no previous CVD were recruited and underwent height and weight measurements before SV and CO.A bioreactance technique was used to measure CO and SV.These were repeated after mean (range) 7(1) days.Results: Mean ÆSD age of patients was 67Æ7 years, height 165Æ9.9cm, weight 74.8Æ18.2kg and BMI 27.2Æ4.7 Kg/m2.Mean SV was 83.6Æ20.6 ml and 81.6Æ 20.3 ml at visit 1 and 2 and CO was 5.7Æ1.1 was 5.7Æ 1.1 L/min respectively.Repeated measures ANOVA showed no significant difference between subject measurements (Both p-values >0.05).The interclass correlation coefficients (ICC's) were 0.93 and 0.99 respectively.The Bland and Altman plot shows no systematic bias with slight random error in both measures (Figure1 &2) Conclusion: These data indicate that CO and SV are reproducible measured using the NICOM device in patients with COPD and maybe appropriate to assess cardiac function in clinical practice. P1.15
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.005 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.004 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".