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MODEL RESULTS OF KIDNEY BURDENS FROM URANIUM INTAKES

2003· article· en· W1968721753 on OpenAlexaff
Jing Chen, D. Meyerhof, Bliss L. Tracy

Bibliographic record

VenueHealth Physics · 2003
Typearticle
Languageen
FieldMedicine
TopicRadiation Dose and Imaging
Canadian institutionsHealth Canada
Fundersnot available
KeywordsUraniumIngestionInhalationKidneyToxicityNatural uraniumInhalation exposureToxicologyRadiochemistryMedicineChemistryPhysiologyEnvironmental chemistryEnvironmental healthInternal medicineBiologyMaterials scienceMetallurgyAnesthesia

Abstract

fetched live from OpenAlex

Uranium is a naturally occurring element, which is both radiologically and chemically toxic. When dealing with intakes of uranium, whether natural or depleted, chemical toxicity to the kidney usually predominates over radiological toxicity. This is especially true for uranium compounds in soluble (inhalation Type F) and moderately soluble (inhalation Type M) forms. To assess chemical toxicity, information on kidney burden per unit intake is required. This study summarizes the kidney burdens per unit intake for common exposures from uranium ingestion and inhalation. ICRP models developed for radiation dosimetry purposes can equally well be used to estimate kidney burdens from uranium intakes. While dosimetric quantities and data are tabulated in ICRP publications, data on uranium burdens in kidney are not explicitly given in these tabulations. In this work, the most recent ICRP models were utilized to generate a compilation of kidney burdens from common intakes. Calculations were made for four age groups from infant to adult. For all age groups, long-term chronic uranium ingestion will result in a kidney burden of 6.6% of daily uranium intake. Comparisons of kidney burdens due to acute ingestion and acute inhalation show that inhaled uranium compounds of Type F and Type M will generally result in higher burdens to kidney compared to the same amount of uranium compounds ingested.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.018
Threshold uncertainty score0.036

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.000
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.052
GPT teacher head0.331
Teacher spread0.279 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations19
Published2003
Admission routes1
Has abstractyes

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