Hepatic Dysfunction During and After Lymphoma Chemotherapy in Patients With Hepatitis C
Bibliographic record
Abstract
BACKGROUND: Hepatitis C is one of the most common causes of chronic liver disease. The literature regarding hepatic dysfunction in Hepatitis C patients during and after chemotherapy is limited. PURPOSE: The goal of this study was to determine the incidence of hepatic dysfunction in Hepatitis C positive patients during and/or after chemotherapy for lymphoma. METHODS: A retrospective chart review was performed. Patients included in the study were anti-hepatitis C virus positive patients treated with chemotherapy for lymphoma at the BC Cancer Agency since 1999. Serum transaminases and bilirubin were the primary criteria used to define and evaluate severity of hepatic dysfunction. Information regarding clinical outcomes was also collected. RESULTS: Forty-one eligible patients were identified. Twenty-four patient charts had sufficient information for review. Four patients met criteria for acute chemotherapy-associated hepatic dysfunction. No deaths secondary to acute hepatic dysfunction were identified. CONCLUSIONS: Hepatic dysfunction in patients with Hepatitis C being treated for lymphoma with chemotherapy occurs but is uncommon.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".