The role of exercise in managing the adverse effects of androgen deprivation therapy in men with prostate cancer
Bibliographic record
Abstract
Background: Androgen deprivation therapy (ADT) is used in the treatment of prostate cancer; however, the side effects of this therapy can be detrimental to a man’s physical and mental health. There has been a growing interest in exercise as a management strategy for many of these problems.Objectives: The aim of this paper is to critically review the ways that resistance and aerobic exercise can ameliorate the adverse effects of ADT in men with prostate cancer. We also provide guidelines for exercise prescription and suggestions to improve adherence.Methods: Studies investigating the effectiveness of exercise for men receiving ADT were reviewed. The online MEDLINE database was searched systematically using appropriate keywords. Citation tracking from these retrieved papers was also used.Major findings: Moderate to high intensity exercise has been shown to reduce the negative impact of many of the side effects of ADT such as muscle loss, decreased strength, fatigue, decreased functional performance, and impaired quality of life.Conclusion: Exercise should be viewed as a primary way to combat the detrimental effects of ADT. Men starting or already undergoing this treatment should be given guidelines for resistance and aerobic exercises.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".