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Firing Patterns in Superior Colliculus of Head-Unrestrained Monkey during Normal and Perturbed Gaze Saccades Reveal Short-Latency Feedback and a Sluggish Rostral Shift in Activity

2009· article· en· W1972096101 on OpenAlexafffund
Woo Young Choi, Daniel Guitton

Bibliographic record

VenueJournal of Neuroscience · 2009
Typearticle
Languageen
FieldNeuroscience
TopicVestibular and auditory disorders
Canadian institutionsMcGill UniversityMontreal Neurological Institute and Hospital
FundersCanadian Institutes of Health Research
KeywordsGazeSuperior colliculusSaccadeNeuroscienceSaccadic maskingPrimateSuperior ColliculiTonic (physiology)PsychologyEye movementCommunicationComputer scienceComputer visionVisual system

Abstract

fetched live from OpenAlex

UNLABELLED: The superior colliculus (SC) encodes a saccade via the spatial position of an ensemble of active neurons on its motor map. Downstream circuits control muscles with the temporal code of firing frequency and duration. The moving hill hypothesis resolves the SC-to-brainstem spatiotemporal transformation (STT) enigma by proposing feedback to the SC which "pushes" a hill of activity (height = frequency) caudorostrally such that its instantaneous position encodes the angular error [gaze-position error (GPE)] between gaze and target. This mechanism, proposed for cat but controversial in primate, has not been tested in the head-unrestrained monkey. We do this here. During large approximately 60 degrees control gaze shifts in the dark, a hill of activity began in the caudal SC and moved rostrally, but too sluggishly to encode veridical GPE. At gaze end the peak had not reached the rostral pole and only arrived there approximately 80 ms later. No moving hill accompanied approximately 20 degrees gaze shifts, in agreement with previous studies of head-fixed monkeys. To investigate feedback to the SC, we perturbed large gaze shifts producing initial and corrective gaze saccades separated by 50-800 ms of gaze immobility, the gaze plateau. Map activity was dramatically remodeled: the sluggishly moving hill stopped during the plateau, at the site encoding the corrective gaze saccade, thereby providing a tonic stationary spatially encoded memory signal of plateau GPE. A burst occurred before the corrective saccade. CONCLUSION: Feedback to map moves activity which encodes a low-pass filtered GPE signal, a process too slow to implement the STT but adequate for corrective gaze saccades.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.712
Threshold uncertainty score0.690

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.275
Teacher spread0.250 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations37
Published2009
Admission routes2
Has abstractyes

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