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Record W1973289401 · doi:10.1136/ebmh.9.3.69

Early intervention has no effect on symptoms in people with first episode, non-affective psychosis, although it may improve overall function and medication adherence

2006· letter· en· W1973289401 on OpenAlexaboutno aff
Berno van Meijel

Bibliographic record

VenueEvidence-Based Mental Health · 2006
Typeletter
Languageen
FieldMedicine
TopicSchizophrenia research and treatment
Canadian institutionsnot available
Fundersnot available
KeywordsPsychosisIntervention (counseling)PsychiatryMedication adherenceMedicineAffect (linguistics)PsychologyClinical psychologyInternal medicineCommunication

Abstract

fetched live from OpenAlex

Garety PA, Craig TKJ, Dunn G, et al . Specialised care for early psychosis: symptoms, social functioning and patient satisfaction—randomised controlled trial. Br J Psychiatry 2006;188:37–45.[OpenUrl][1][Abstract/FREE Full Text][2] Q Does early intervention improve symptoms, treatment adherence, and functioning in people with early stage psychosis? ### ![Graphic][3] Design: Randomised controlled trial. ### ![Graphic][4] Allocation: Concealed. ### ![Graphic][5] Blinding: Unclear. ### ![Graphic][6] Follow up period: 18 months. ### ![Graphic][7] Setting: Inner city borough of London (Lambeth), UK; recruitment from January 2000 to June 2001. ### ![Graphic][8] Patients: 144 people (aged 16–40 years) with first episode, non-affective psychosis (ICD-10). Exclusions: substance abuse disorders, organic psychosis. ### ![Graphic][9] Intervention: Specifically adapted interventions, including cognitive behavioural therapy, medication management, vocational support, and family interventions provided by early onset psychosis mental health team. Comparator: standard generic community services; no special training or specially adapted support. ### ![Graphic][10] Outcomes: Clinical state (Positive and Negative Syndrome Scale (PANSS)); overall functioning (Global Assessment of Functioning (GAF)); depression (Calgary Depression Rating); treatment … [1]: {openurl}?query=rft.jtitle%253DThe%2BBritish%2BJournal%2Bof%2BPsychiatry%26rft.stitle%253DBr.%2BJ.%2BPsychiatry%26rft.aulast%253DGARETY%26rft.auinit1%253DP.%2BA.%26rft.volume%253D188%26rft.issue%253D1%26rft.spage%253D37%26rft.epage%253D45%26rft.atitle%253DSpecialised%2Bcare%2Bfor%2Bearly%2Bpsychosis%253A%2Bsymptoms%252C%2Bsocial%2Bfunctioning%2Band%2Bpatient%2Bsatisfaction%253A%2BRandomised%2Bcontrolled%2Btrial%26rft_id%253Dinfo%253Adoi%252F10.1192%252Fbjp.bp.104.007286%26rft_id%253Dinfo%253Apmid%252F16388068%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/ijlink?linkType=ABST&journalCode=bjprcpsych&resid=188/1/37&atom=%2Febmental%2F9%2F3%2F69.atom [3]: /embed/inline-graphic-1.gif [4]: /embed/inline-graphic-2.gif [5]: /embed/inline-graphic-3.gif [6]: /embed/inline-graphic-4.gif [7]: /embed/inline-graphic-5.gif [8]: /embed/inline-graphic-6.gif [9]: /embed/inline-graphic-7.gif [10]: /embed/inline-graphic-8.gif

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.005
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.018
Threshold uncertainty score0.059

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.005
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0020.003
Bibliometrics0.0010.001
Science and technology studies0.0000.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0180.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.318
Teacher spread0.298 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2006
Admission routes1
Has abstractyes

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