Influence of plasma lipid changes in response to 17β‐oestradiol stimulation on plasma growth hormone, somatostatin, and thyroid hormone levels in immature rainbow trout
Bibliographic record
Abstract
Plasma total lipids were significantly higher in 17β‐oestradiol(E2)‐treated immature rainbow troutOncorhynchus mykissat week 4 after implantation, due to increases in polar and neutral lipids. The lipid classes responding were phosphatidylcholine, phosphatidylinositol, phosphatidylethanolamine, sterols and sterol esters, in a proportion that approximately reflected the increase in plasma vitellogenin (VtG) levels as measured by a non‐competitive enzyme‐linked immunosorbent assay (ELISA). Plasma non‐esterified fatty acids and triacylglycerol were not affected by E2treatment. Plasma growth hormone GH levels were increased, and plasma somatostatin‐14 (SRIF) levels decreased in E2‐treated fish, responses which could be secondary to elevated plasma lipid (VtG) content, although a direct E2action on somatotroph function is possible. Plasma T4concentrations were not affected by E2treatment, but plasma T3concentrations were significantly lower than in controls 1 week after implantation when plasma E2concentrations were the highest; this is in support of the hypothesis that E2has a suppressive action on T3production.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".