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Record W1976571746 · doi:10.2337/dc12-1368

Balancing Weight and Glucose in Gestational Diabetes Mellitus

2012· letter· en· W1976571746 on OpenAlexaff
Edmond A. Ryan

Bibliographic record

VenueDiabetes Care · 2012
Typeletter
Languageen
FieldMedicine
TopicGestational Diabetes Research and Management
Canadian institutionsUniversity of Alberta
Fundersnot available
KeywordsMedicineGestational diabetesOverweightPregnancyDiabetes mellitusFetal macrosomiaObstetricsPopulationObesityShoulder dystociaEndocrinologyGestationEnvironmental health

Abstract

fetched live from OpenAlex

The instinctive concern of a pregnant woman for her baby creates a receptive environment for advice, and so it is particularly important that medical recommendations during pregnancy should be factual and reasoned. In this issue of Diabetes Care , Black et al. (1) have shown in a group of women who did not have gestational diabetes mellitus (GDM) by traditional thresholds that maternal overweight and obesity accounted for 21.6% of large-for-gestational-age (LGA) infants, and when GDM as defined by the newer American Diabetes Association (ADA) criteria was added into the equation, the combination was responsible for 23.3% of neonatal LGA. This article is a helpful addition to the debate balancing the impact of maternal adiposity or hyperglycemia on the risk of LGA in the baby. The historical poor outcomes of pregestational diabetes are testimony to the harmful effects of high glucose in early pregnancy as manifest by congenital malformations and in later pregnancy as evidenced by LGA and its consequences. Interestingly, over time with better glucose control the risk for congenital malformations has decreased but not the risk for LGA (2). A proportion of women with no known diabetes have a pancreas that cannot respond to the increased insulin requirements of pregnancy, and they therefore develop GDM. These women have more LGA and shoulder dystocia (3), and there is good evidence that treatment reduces these problems (4). Overweight mothers also have less favorable outcomes. In population studies, obesity is associated with more LGA, gestational hypertension, preeclampsia, GDM, and extra pounds retained postpartum, whereas excess weight gain during pregnancy is more closely associated with preeclampsia, LGA, and retained weight postpartum (5–7). Women who have bariatric …

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.006
metaresearch head score (Gemma)0.028
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.008
Threshold uncertainty score0.031

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0060.028
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0020.002
Science and technology studies0.0010.003
Scholarly communication0.0040.004
Open science0.0020.002
Research integrity0.0080.014
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.248
Teacher spread0.238 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations9
Published2012
Admission routes1
Has abstractyes

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