Peroperative Myocardial Ischemia and Citrate Administration: Cardiovascular Adaptability in Conscious Dogs
Bibliographic record
Abstract
Since the hemodynamic response elicited by the administration of citrate is sensitive to alterations in the baseline cardiovascular status, we have investigated the consequences of peroperative myocardial ischemia upon this hemodynamic response. 19 dogs equipped with an electromagnetic flow probe positioned around the ascending aorta served as control (group I). 16 dogs were equipped similarly and in addition submitted to 1 h of myocardial ischemia combined with topical cardiac hypothermia (group II). Hemodynamic studies were carried out 3 h postoperatively and then daily for 1 month, before and during rapid intravenous administration of citrate. From baseline hemodynamic data, cardiac failure was only evident 3 h postoperatively in group II. Transient hypotension and myocardial depression resulted from administration of citrate in both groups with no evidence of peripheral vasodilation. Hypotension and the negative inotropic response were more pronounced in the presence of cardiac failure following peroperative myocardial ischemia. Long-term studies indicate that global myocardial ischemia did not interfere with the cardiovascular adaptability to this pharmacologic interference.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".