Effects of parasitism on the octopamine content of the central nervous system of<i>Manduca sexta</i>: a possible mechanism underlying host behavioural change
Bibliographic record
Abstract
The parasitic wasp Cotesia congregata lays its eggs inside the larva of Manduca sexta (tobacco hornworm). Beginning about 12 h before the wasp larvae emerge from the host, host feeding and locomotion decline. The octopamine content of the central nervous system (CNS) of parasitized hosts was measured using high-performance liquid chroma tography with electrochemical detection. Concomitant with the decrease in host feeding and locomotion, the octopamine content of the host's brain (supra- and sub-esophageal ganglia), thoracic ganglia, and abdominal ganglia increased. In nonparasitized M. sexta, the octopamine content of the CNS did not change significantly during moult sleep, a stage in which the behaviour superficially resembles that of M. sexta after the wasps have emerged. Neither result is consistent with the hypothesis that the octopamine content within the CNS is lower in inactive insects. Nevertheless, the close temporal correlation between the change in host behaviour and CNS octopamine content suggests that alterations in the functioning of the octopaminergic system may play a role in depressing host feeding and (or) locomotion.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".