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Record W1978800900 · doi:10.1159/000206113

Persistent Cold Agglutinins in AIDS and Related Disorders

2009· article· en· W1978800900 on OpenAlexaff
W. Pruzanski, D. Roelcke, E. Donnelly, L.-C. Lui

Bibliographic record

VenueActa Haematologica · 2009
Typearticle
Languageen
FieldImmunology and Microbiology
TopicT-cell and Retrovirus Studies
Canadian institutionsWellesley InstituteUniversity of Toronto
Fundersnot available
KeywordsCold AgglutininMedicineAntibodyImmunologyAIDS-related complexLymphoproliferative disordersAnemiaGastroenterologyInternal medicineHuman immunodeficiency virus (HIV)Viral diseaseLymphoma

Abstract

fetched live from OpenAlex

Eighty-one homosexual patients positive for HTLV-III antibody, including 19 with AIDS, 20 with chronic lymphadenopathy syndrome, 10 with AIDS-related complex (ARC) and 32 symptom-free individuals were assessed for the presence of cold agglutinins (CA). In 12 cases, CA were found; 4, 4, 2 and 2, respectively, in each of the above mentioned groups. Seven anti-I, 4 anti-i and 1 anti-Gd CA were identified. In 11 of 12 patients, CA were persistent. There were no differences between CA-negative and CA-positive patients with regard to the presence of other antibodies, anemia, frequency of intercurrent infections or development of lymphoproliferative neoplasia. It can be concluded that persistent synthesis of CA may be associated with the HTLV-III infection.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.215
Teacher spread0.206 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations25
Published2009
Admission routes1
Has abstractyes

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