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A Simulation of the Effect of Blood in the Mouth on Breath Alcohol Concentrations of Drinking Subjects

2002· article· en· W1981852132 on OpenAlexaffvenue
J.G. Wigmore, M.P. Wilkie

Bibliographic record

VenueCanadian Society of Forensic Science Journal · 2002
Typearticle
Languageen
FieldMedicine
TopicAlcohol Consumption and Health Effects
Canadian institutionsHealth Sciences Centre
Fundersnot available
KeywordsAlcoholBlood alcoholMedicineVolunteerAnesthesiaChemistryPoison controlBiology

Abstract

fetched live from OpenAlex

After consuming lunch, twenty-six male subjects ingested alcohol ad libitum over approximately one hour. At least 1.5 hours after drinking ceased, the subjects provided breath samples into a Breathalyzer® Model 900 or 900A. Immediately after providing the breath samples, blood was collected from the cubital vein using a sterile disposable plastic syringe. Part of the blood sample (3–10 mL) was placed into a blood tube containing 1 % sodium fluoride and 0.5 % sodium citrate and was analysed for alcohol by headspace gas chromatography. The remaining blood (3–10 mL) was placed in the subject's mouth for up to 30 seconds and then swallowed or expectorated. A second Breathalyzer test was conducted within ten minutes of the first. The blood alcohol concentrations of the subjects averaged 0.095 g/dL and ranged between 0.044 to 0.168 g/dL. The untruncated Breathalyzer results were significantly lower after introducing blood into the mouth (p=0.017). When these Breathalyzer results were truncated to two decimal places, however, these slight differences were eliminated. In addition, when the initial Breathalyzer results were compared to the blood alcohol concentrations the apparent blood breath ratios averaged 2319, with a range of 1947:1 to 2654:1. We conclude that blood in the mouth does not lead to an overestimation of the breath alcohol concentration of drinking subjects.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.038
Threshold uncertainty score0.075

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.056
GPT teacher head0.331
Teacher spread0.275 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations8
Published2002
Admission routes2
Has abstractyes

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Same venueCanadian Society of Forensic Science JournalSame topicAlcohol Consumption and Health EffectsFrench-language works237,207