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Record W1981909269 · doi:10.1021/om050982m

Hydridodimethylplatinum(IV) Complexes with Bis(pyridine) Ligands:  Effect of Chelate Ring Size on Reactivity

2006· article· en· W1981909269 on OpenAlexaff
Fenbao Zhang, E.M. Prokopchuk, M.E. Broczkowski, Michael C. Jennings, Richard J. Puddephatt

Bibliographic record

VenueOrganometallics · 2006
Typearticle
Languageen
FieldChemistry
TopicAsymmetric Hydrogenation and Catalysis
Canadian institutionsWestern University
Fundersnot available
KeywordsChemistryReactivity (psychology)PyridineMedicinal chemistryPlatinumLigand (biochemistry)Ring (chemistry)Methyl iodideChelationProtonationOxidative additionIodideStereochemistryCrystallographyInorganic chemistryOrganic chemistryCatalysis

Abstract

fetched live from OpenAlex

The effect of changing the bite angle of the dipyridyl ligand LL on the reactivity of the dimethylplatinum(II) complexes [PtMe 2 (LL)] has been studied, by comparing complexes with the ligands LL = di-2-pyridylamine (DPA) or di-2-pyridyl ketone (DPK), which form a six-membered chelate ring, to compounds with 2,2‘-bipyridyl derivatives, which form a five-membered chelate ring. The complex [PtMe 2 (DPA)] undergoes easy oxidative addition of methyl iodide to give the corresponding platinum(IV) complex [PtIMe 3 (DPA)]. Both [PtMe 2 (DPA)] and [PtMe 2 (DPK)] are protonated by acids HX at low temperature to give the hydridodimethylplatinum(IV) complexes [PtHXMe 2 (NN)] and [PtH(S)Me 2 (NN)]X (S = solvent), which can exist in two isomeric forms with H trans to X or N. The structure of the complex [PtHClMe 2 (DPK)] was determined crystallographically. In a solution containing excess CD 3 OD, extensive hydrogen/deuterium exchange occurs into the methylplatinum groups and methane product at low temperature, indicating very easy reversibility of the exchange between hydridomethylplatinum(IV) and (methane)platinum(II) complexes. The hydridomethylplatinum(IV) complexes reductively eliminate methane at room temperature in solution but have significantly higher thermal stability and undergo more extensive H−D exchange than when NN = 2,2‘-bipyridyl. The reaction of [PtMe 2 (DPA)] with excess HCl gave [PtCl 2 (DPA)], and the reaction of [PtMe 2 (DPK)] with excess CF 3 SO 3 H gave the aqua complex [Pt(OH 2 ) 2 (DPK)](CF 3 SO 3 ) 2 or the binuclear hydroxo complex [Pt 2 (μ-OH) 2 (DPK) 2 ](CF 3 SO 3 ) 2, depending on the experimental conditions.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.071
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.005
GPT teacher head0.208
Teacher spread0.203 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations77
Published2006
Admission routes1
Has abstractyes

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