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Record W1982632078 · doi:10.1093/arclin/acp111

Age Corrections and Dementia Classification Accuracy

2010· article· en· W1982632078 on OpenAlexafffund
Megan E. O’Connell, Holly Tuokko

Bibliographic record

VenueArchives of Clinical Neuropsychology · 2010
Typearticle
Languageen
FieldMedicine
TopicDementia and Cognitive Impairment Research
Canadian institutionsUniversity of VictoriaUniversity of Saskatchewan
FundersHealth CanadaCanadian Institutes of Health ResearchAlzheimer SocietyMedical Research CouncilPfizer CanadaUniversity of OttawaMichael Smith Health Research BCUniversity of VictoriaPfizer
KeywordsDementiaRaw scorePercentileNormativeCutoffRaw dataContrast (vision)Diagnostic accuracyMedicineStatisticsAudiologyPsychologyMathematicsArtificial intelligenceInternal medicineComputer scienceDisease

Abstract

fetched live from OpenAlex

In contrast to expectations, demographic corrections to reduce biases against those of advanced age or few years of education does not universally improve diagnostic classification accuracy. Age corrections may be particularly problematic because age is also a risk factor for a dementia diagnosis. We found that simulating increased risk for dementia based on demographic variables, such as age, reduced the overall classification accuracy for demographically corrected simulated scores relative to the raw, uncorrected test scores. In clinical data with a small magnitude of association between age and dementia diagnosis, we found equivalent overall classification accuracy for demographically corrected and raw test scores. Regardless of the overall classification accuracy results, cutoff comparisons (16th and 9th percentiles) in clinical and simulated data demonstrated that for the most part, the sensitivity of raw scores was higher than the sensitivity of demographically corrected scores, but the specificity of scores corrected with normative data was superior.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.331
Threshold uncertainty score0.292

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.079
GPT teacher head0.459
Teacher spread0.379 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations35
Published2010
Admission routes2
Has abstractyes

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