LEP gene allelic polymorphism in a subpopulation of Ayrshire cattle
Bibliographic record
Abstract
Genotyping of the leptin gene locus (LEP) (SNP: R25C, Y7F, and A80V) has been conducted in cows from two cattle droves (n = 106 and n = 34) and in bulls of Ayrshire cattle (n = 9) that are intensively used at present for artificial insemination in cows in Krasnodar krai. The absence of A80V polymorphism (C --> T at position 95691973 bp of leptin gene) has been established in the genotypes of Ayrshire cattle as compared to Holstein cattle; however, the F allele (Y7F site A --> T at position 95689996 bp of LEP gene), which is rare in Holstein cattle, was shown to be frequent in Ayrshire cows and producer bulls (with a frequency of 0.22-0.79). The heterozygosity did not exceed 0.11 in adult animals, which might be evidence of a decreased vitality in animals bearing the FF genotype. Moreover, the CC genotype (R25C site T-C at position 95690050 bp of LEP gene) was revealed to be linked to the YY genotype (Y7F site) in 97% of cases from possible combinations of the CCYY, CCYF, and CCFF genotypes, while the FF genotype (Y7F site) was observed to be linked to the RR genotype (R25C site) in 100% of cases of possible combinations of FFCC, FFRC, and FFRR genotypes.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".