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Record W1984366888 · doi:10.1016/s0960-9776(02)00284-9

A case–control study of breast cancer and dietary intake of individual fatty acids and antioxidants in Montreal, Canada

2003· article· en· W1984366888 on OpenAlex
André Nkondjock, Bryna Shatenstein, Parviz Ghadirian

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.
aboutThe title or abstract carries a Canadian signal from the geographic lexicon.

Bibliographic record

VenueThe Breast · 2003
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicCancer, Lipids, and Metabolism
Canadian institutionsCentre Hospitalier de l’Université de MontréalInstitute of Population and Public HealthUniversity of OttawaInstitut Universitaire de Gériatrie de MontréalUniversité de Montréal
FundersNational Cancer InstituteMedical Research Council Canada
KeywordsMedicineBreast cancerOdds ratioPolyunsaturated fatty acidQuartileCase-control studyConfidence intervalArachidonic acidInternal medicinePhysiologyCancerVitamin EEndocrinologyPopulationFatty acidAntioxidantEnvironmental healthBiochemistry

Abstract

fetched live from OpenAlex

This case-control study was conducted among French-Canadians to assess the association between breast cancer risk and specific fatty acids, and to investigate if breast cancer risk associated with individual polyunsaturated fatty acids differs in regard to antioxidant intakes. A total of 414 cases and 429 population-based controls were interviewed between 1989 and 1993. Dietary intake was assessed by a food-frequency questionnaire. No overall association was found between specific fatty acids and breast cancer risk, after adjustment for risk factors and total energy intake. In postmenopausal women with low vitamin E intake, there was an inverse and dose-dependent relationship between arachidonic acid and breast cancer risk [odds ratio (OR)=0.41; 95% confidence interval (CI) (0.20-0.82); P=0.02], while those with high vitamin E intake exhibited a significantly elevated risk [OR=2.46; 95% CI (1.12-5.39); P=0.024] when comparing the upper to the lower quartiles. The possible role of the interaction effect between arachidonic acid and vitamin E in breast cancer risk requires further investigation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.425
Threshold uncertainty score0.595

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.226
Teacher spread0.217 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it