MétaCan
Menu
Back to cohort
Record W1984366888 · doi:10.1016/s0960-9776(02)00284-9

A case–control study of breast cancer and dietary intake of individual fatty acids and antioxidants in Montreal, Canada

2003· article· en· W1984366888 on OpenAlexafffundabout
André Nkondjock, Bryna Shatenstein, Parviz Ghadirian

Bibliographic record

VenueThe Breast · 2003
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicCancer, Lipids, and Metabolism
Canadian institutionsCentre Hospitalier de l’Université de MontréalInstitute of Population and Public HealthUniversity of OttawaInstitut Universitaire de Gériatrie de MontréalUniversité de Montréal
FundersNational Cancer InstituteMedical Research Council Canada
KeywordsMedicineBreast cancerOdds ratioPolyunsaturated fatty acidQuartileCase-control studyConfidence intervalArachidonic acidInternal medicinePhysiologyCancerVitamin EEndocrinologyPopulationFatty acidAntioxidantEnvironmental healthBiochemistry

Abstract

fetched live from OpenAlex

This case-control study was conducted among French-Canadians to assess the association between breast cancer risk and specific fatty acids, and to investigate if breast cancer risk associated with individual polyunsaturated fatty acids differs in regard to antioxidant intakes. A total of 414 cases and 429 population-based controls were interviewed between 1989 and 1993. Dietary intake was assessed by a food-frequency questionnaire. No overall association was found between specific fatty acids and breast cancer risk, after adjustment for risk factors and total energy intake. In postmenopausal women with low vitamin E intake, there was an inverse and dose-dependent relationship between arachidonic acid and breast cancer risk [odds ratio (OR)=0.41; 95% confidence interval (CI) (0.20-0.82); P=0.02], while those with high vitamin E intake exhibited a significantly elevated risk [OR=2.46; 95% CI (1.12-5.39); P=0.024] when comparing the upper to the lower quartiles. The possible role of the interaction effect between arachidonic acid and vitamin E in breast cancer risk requires further investigation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.018
Threshold uncertainty score0.129

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.003
Science and technology studies0.0040.001
Scholarly communication0.0010.000
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.226
Teacher spread0.217 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations48
Published2003
Admission routes3
Has abstractyes

Explore more

Same venueThe BreastSame topicCancer, Lipids, and MetabolismFrench-language works237,207