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Record W1984568232 · doi:10.1007/s00439-013-1383-3

Genome-wide association study of subtype-specific epithelial ovarian cancer risk alleles using pooled DNA

2013· article· en· W1984568232 on OpenAlex
Madalene A. Earp, Linda E. Kelemen, Anthony M. Magliocco, Kenneth D. Swenerton, Georgia Chenevix‐Trench, Yi Lu, Alexander Hein, Arif B. Ekici, Matthias W. Beckmann, Peter A. Fasching, Diether Lambrechts, Evelyn Despierre, Ignace Vergote, Sandrina Lambrechts, Jennifer A. Doherty, Mary Anne Rossing, Jenny Chang‐Claude, Anja Rudolph, Grace Friel, Kirsten B. Moysich, Kunle Odunsi, Lara Sucheston‐Campbell, Galina Lurie, Marc T. Goodman, Michael E. Carney, Pamela J. Thompson, Ingo B. Runnebaum, Matthias Dürst, Peter Hillemanns, Thilo Dörk, Natalia Antonenkova, Natalia Bogdanova, Arto Leminen, Heli Nevanlinna, Liisa M. Pelttari, Ralf Bützow, Clareann H. Bunker, Francesmary Modugno, Robert P. Edwards, Roberta B. Ness, Andreas du Bois, Florian Heitz, Ira Schwaab, Philipp Harter, Beth Y. Karlan, Christine Walsh, Jenny Lester, Allan Jensen, Susanne K. Kjær, Claus Høgdall, Estrid Høgdall, Lene Lundvall, Thomas A. Sellers, Brooke L. Fridley, Ellen L. Goode, Julie M. Cunningham, Robert A. Vierkant, Graham G. Giles, Laura Baglietto, Gianluca Severi, Melissa C. Southey, Dong Liang, Xifeng Wu, Karen H. Lu, Michelle A.T. Hildebrandt, Douglas A. Levine, Maria Bisogna, Joellen M. Schildkraut, Edwin S. Iversen, Rachel Palmieri Weber, Andrew Berchuck, Daniel W. Cramer, Kathryn L. Terry, Elizabeth M. Poole, Shelley S. Tworoger, Elisa V. Bandera, Urmila Chandran, Irene Orlow, Sara H. Olson, Elisabeth Wik, Helga B. Salvesen, Line Bjørge, Mari K. Halle, Anne M. van Altena, Katja K.H. Aben, Lambertus A. Kiemeney, Leon F.A.G. Massuger, Tanja Pejović, Yukie T. Bean, Cezary Cybulski, Jacek Gronwald, Jan Lubiński, Nicolas Wentzensen, Louise A. Brinton, Jolanta Lissowska, Montserrat García‐Closas, Ed Dicks, Joe Dennis, Douglas F. Easton, Honglin Song, Jonathan P. Tyrer, Paul D.P. Pharoah, Diana Eccles, Ian Campbell, Alice S. Whittemore, Valerie McGuire, Weiva Sieh, Joseph H. Rothstein, James M. Flanagan, James Paul, Robert Brown, Catherine M. Phelan, Harvey A. Risch, Steven A. Narod, Argyrios Ziogas, Hoda Anton‐Culver, Aleksandra Gentry‐Maharaj, Usha Menon, Simon A. Gayther, Susan J. Ramus, Anna H. Wu, Celeste Leigh Pearce, Malcolm C. Pike, Agnieszka Dansonka‐Mieszkowska, Iwona K. Rzepecka, Lukasz M. Szafron, Jolanta Kupryjańczyk, Linda S. Cook, Nhu D. Le, Angela Brooks‐Wilson

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenueHuman Genetics · 2013
Typearticle
Languageen
FieldMedicine
TopicOvarian cancer diagnosis and treatment
Canadian institutionsWomen's College HospitalUniversity of TorontoLunenfeld-Tanenbaum Research InstituteMount Sinai HospitalUniversity of British ColumbiaUniversity of CalgaryCanada's Michael Smith Genome Sciences CentreSimon Fraser UniversityBC Cancer Agency
FundersNational Center for Research ResourcesCancer Council VictoriaCancer Council South AustraliaNational Cancer InstituteHelse VestCancer Council TasmaniaNational Institutes of HealthCancer Council NSWCancer Research UKRutgers Cancer Institute of New JerseyWorkSafeBCBundesministerium für Bildung und ForschungLon V. Smith FoundationDeutsches KrebsforschungszentrumHelsingin ja Uudenmaan SairaanhoitopiiriCanadian Institutes of Health ResearchCancer Council QueenslandFred C. and Katherine B. Andersen Foundation
KeywordsGenome-wide association studySerous fluidBiologyOdds ratioGenotypeOvarian cancerAlleleGenetic associationOncologyEpithelial ovarian cancerCase-control studyGeneticsInternal medicineCancerGeneSingle-nucleotide polymorphismMedicine

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.008
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.034
GPT teacher head0.286
Teacher spread0.251 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it