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Record W1985485420 · doi:10.1118/1.2965980

Sci‐Fri PM: Planning‐08: Zero diffusion radiochromic genipin‐gelatin dosimeter

2008· article· en· W1985485420 on OpenAlexaff
K Jordan

Bibliographic record

VenueMedical Physics · 2008
Typearticle
Languageen
FieldPhysics and Astronomy
TopicAdvanced Radiotherapy Techniques
Canadian institutionsLondon Health Sciences CentreWestern University
Fundersnot available
KeywordsMaterials scienceGelatinDosimeterGenipinCuvetteDosimetryOpticsIrradiationSulfuric acidDistilled waterAnalytical Chemistry (journal)DiffusionRadiationNuclear medicineChemistryChromatography

Abstract

fetched live from OpenAlex

PURPOSE: To develop a zero diffusion radiochromic hydrogel by cross-linking gelatin polymers with genipin, for three-dimensional (3-D) radiation dosimetry. METHOD AND MATERIALS: Gelatin and genipin were dissolved in distilled water and continuously stirred at 40C for thee hours and then sulfuric acid was acid prior to placing gel in containers. Concentrations of genipin, gelatin and sulfuric acid were varied to determine the optimal gel sensitivity for optical computed tomography (CT). Photon beams (4 MV x-rays, 1×1, 2×2, 3×3 cm) irradiated a 10 cm diameter cylinder of gel. Using a cone beam optical CT scanner at λ = 590 nm, zero diffusion was observed by recording sequential 3D scans separated by 18 hours. Additional evidence was provided by sequential transmission photographs of a cuvette containing a sample that had been exposed to a 0.8 mm diameter, 1 mW, 594 nm, He-Ne laser beam and photobleached. RESULTS: Radiochromic bleaching is a fast process, complete within seconds of termination of irradiation. Dose sensitivity increases with cross- linking density and sulfuric acid concentration. The initial optical density limits dose sensitivity, requiring approximately 30 Gy for 10 cm diameter samples to have reasonable contrast. More sensitive but darker gels require smaller samples. A comparison of profiles through 3D reconstructed dose distribution showed identical profiles for a time interval of 18 hours. Visually the sample maintained this image for six months when stored at 4C in a dark refrigerator. Transmission photographs of the laser beam image recorded by photobleaching remained constant when stored a 23 C in the dark for ten months. CONCLUSION: Radiochromic genipin gelatin gels form a permanent and stable image when protected from bright visible light. This result is a new, non-toxic material for 3D dosimetry.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.017
Threshold uncertainty score0.056

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0170.006

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.280
Teacher spread0.265 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations14
Published2008
Admission routes1
Has abstractyes

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