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Record W1985837373 · doi:10.1088/0031-9155/54/15/008

Characteristics of time-domain optical coherence tomography profiles generated from blood–saline mixtures

2009· article· en· W1985837373 on OpenAlexaff
Dan P. Popescu, Michael G. Sowa

Bibliographic record

VenuePhysics in Medicine and Biology · 2009
Typearticle
Languageen
FieldEngineering
TopicOptical Coherence Tomography Applications
Canadian institutionsNational Research Council Institute for Biodiagnostics
Fundersnot available
KeywordsOptical coherence tomographyAttenuationSIGNAL (programming language)OpticsMaterials scienceScatteringTime domainBiomedical engineeringPhysicsMedicine

Abstract

fetched live from OpenAlex

Time-domain optical coherence tomography (OCT) employing a 1300 nm broadband source is used to study flowing blood-saline mixtures with blood concentration ranging from 20% to 100%. The study emphasizes the characteristics of the recorded OCT signal and its connection with the properties of the corresponding fluids. There are three regions with distinct properties along the compounded OCT profiles showing the signal dependence on depth. The recorded OCT signal increases for the first 80 microm into the fluid. The flow characteristics of the solution and the average spatial orientation of the blood cells can be extracted from this region of the OCT profile. In the second region, the OCT signal decreases with depth into the sample. An admixture of quasi-ballistic light detected after a single reflection and light recorded after undergoing multiple-scattering interactions with blood cells contributes to the signal recorded in this region. As a consequence, the attenuation of OCT signal with depth into the sample shows a weak dependence on the concentration of blood over this region. The third region starts at a depth of approximately 0.6 mm within all the studied blood-saline mixtures. OCT signal recorded from this region is dominated by light detected after multiple-scattering interactions with blood cells. This region of the OCT profile is characterized by a reduced rate of attenuation with depth compared to the rate recorded along the second region of the compounded profile. A geometrical method is used to estimate the contribution from multiple-scattered light to the OCT signal. The multiple-scattered component shows a parabolic dependence on blood concentration with a maximum contribution at a blood concentration of 55%.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.719
Threshold uncertainty score0.454

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.044
GPT teacher head0.298
Teacher spread0.254 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2009
Admission routes1
Has abstractyes

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